Doxycycline is a broad-spectrum antibiotic that falls under the tetracycline class of drugs. It blocks protein synthesis, killing bacteria and protozoa. The drug was first patented in 1957 and became available as a pharmaceutical in 1967. It is medically approved for the treatment of various conditions such as acne, bacterial pneumonia, chlamydia, cholera, Lyme disease, Rocky Mountain spotted fever, and syphilis.
It is possible that you have been diagnosed with acne or any other bacterial infection, and you were advised to take Doxycycline. However, you aren’t sure if you should take it since you have heard negative feedback (like “doxycycline ruined my life”) about the drug and that the drug has been described as a horrible drug for people.
Doxycycline Side Effects
Some of the most common side effects of Doxycycline include Nausea, vomiting, Diarrhea, Loss of appetite, Sensitivity to sunlight, upset stomach and abdominal pain, Yeast infections and Headache.
In some cases, Doxycycline can also cause more serious side effects, including Liver damage, Increased bleeding risk, Allergic reactions, such as hives, difficulty breathing, and swelling of the face, lips, tongue, or throat and Mood or behavior changes.
It’s imperative to note that these side effects are not felt by everyone who takes doxycycline. Most people will not experience serious problems. However, if you experience any concerning side effects while taking Doxycycline, it is important to stop administering the drug and seek medical attention immediately. Your doctor will be able to determine the cause of your symptoms and determine the best course of action.
Doxycycline Ruined My Life; Why Patients Giving This Statement?
Recently many questions are arising regarding doxycycline, some key queries are following:
- can doxycycline make you angry?
- Does doxycycline make you depressed?
- Can doxycycline cause anxiety?
Let, me discuss all in detail with the help of some recent research studies and clinical Trials
Does Doxycycline Make You Angry?
As of now, there is limited evidence to suggest that Doxycycline can cause adverse neuropsychiatric reactions such as depression, suicidality, and anxiety. However, it’s possible that these types of reactions are not widely reported by doxycycline users or are not recognized by medical doctors.
It may be that the frequency and severity of depression, suicidality, and anxiety as side effects of Doxycycline are greater than previously thought. The following are examples of case reports and studies that document these types of reactions as adverse effects of Doxycycline.
According to one of the studies, 91 cases of psychosis or hallucinations have been reported from doxycycline in over 6,000 reports. This suggests a potential link between Doxycycline use and sudden and severe psychiatric problems. Furthermore, the study found that at least 14 other antibiotics showed an increased risk of these types of side-effects. This indicates that this issue may not be unique to Doxycycline and could affect a wider range of antibiotics.
It is critical to note that while this study suggests a potential link between antibiotics and psychiatric side-effects, it does not establish a cause-and-effect relationship. Further research would be needed to determine the nature of the relationship and establish more appropriate recommendations for healthcare providers and patients.
Can Doxycycline Cause Anxiety?
In some cases, doxycycline can cause anxiety or depression.
Certain individuals who feel abnormal mood states have been known to experience anxiety from doxycycline.
Doxycycline’s anxiety symptoms require immediate medical attention because they can mimic some of its side effects.
Does Doxycycline Make You Depressed And May Lead To Suicide?
Some studies reported depression and suicide related side effects of Doxycycline, which I have elaborated below:
In a case series of three young individuals, neither of whom had a history of mental illness, doxycycline was prescribed for skin conditions, but in two of the cases, the individuals developed suicidal ideation with a subsequent suicide attempt. This individual was a heterozygote for the CYP2C19 cytochrome p450 enzyme with a low cytochrome p450 enzyme activity, and two of his siblings had previously developed severe anxiety while taking doxycycline, and he was suffering from this type of disorder during that time as well. It has been reported that another patient who was previously taking a lower dose of doxycycline had previously developed mood difficulties that resolved once it was discontinued. Thirdly, in the case of the third individual, there has been a complete resolution of symptoms as a result of discontinuation of doxycycline without the need for any psychotropic medication.
Read More: Doxycycline and suicidality
This is how healthsoothe described the term “doxycycline ruined my life”
What Are Doxycycline Alternatives?
Many patients are afraid of this statement “doxycycline ruined my life” and looking for alternative options.
Always ensure the rational use of Doxycyline and all antibiotics or otherwise consider the following alternatives prescribed by a health care practitioner:
- Minocycline: Another tetracycline antibiotic with comparable effectiveness and side effects.
- Amoxicillin: This is a penicillin-type antibiotic effective against a wide range of bacterial infections, including respiratory tract infections, skin infections, and urinary tract infections.
- Azithromycin: This is a macrolide antibiotic that effectively fights a wide range of bacteria, resistant to other antibiotics.
- Ciprofloxacin: This is a fluoroquinolone antibiotic having similar indications.
It is important to note that these are just a few of the many alternatives that are available to doxycycline. As a result of your medical history, symptoms, and other factors, your doctor can assist you in determining the best option for you.
Doxycycline has various side effects including headaches, discomfort, anxiety which may lead to depression as of few case reports and research studies. However, more research is needed to reach a definitive conclusion. You should always speak with your health care professional before prescribing an antibiotic appropriate for you. Rational use of drugs involves many factors including patient history, antibiotic resistance report, concomitant diseases, and drug interactions. Always consult your doctor or clinical pharmacist to make the right Antibiotic choice. If you experience any side effects, you should consult your health care provider immediately.